ISSN: 1307-279X
Yeditepe Medical Journal
SURGICAL MANAGEMENT OF PHYLLODES TUMORS OF BREAST [YMJ]
YMJ. 2013; 7(26): 613-618

SURGICAL MANAGEMENT OF PHYLLODES TUMORS OF BREAST

Deniz Eren Boler1, Cihan Uras2, Ercument Gurluler1, Hamit Karayagız3, Yesim Saglıcan4, Alihan Gurkan1, Neslihan Cabıoglu1
1Department of General Surgery, Acıbadem University Medical Faculty, İstanbul, Turkey
2Department of General Surgery, İstanbul University Cerrahpaşa Medical Faculty & Acıbadem Bakırköy Hospital, İstanbul, Turkey
3Department of General Surgery, International Hospital, İstanbul, Turkey
4Department of Pathology Acıbadem University Medical Faculty, İstanbul, Turkey

Objectives: Phyllodes tumors are rare breast tumors and challenges still exist in diagnosis and treatment. In this study we aimed to present our surgical approach and results of the patients with definitive diagnosis of phyllodes tumors. Patients and Method: Medical records of thirteen patients with final pathology of phyllodes tumor who had been operated in Acıbadem Bakırköy, Maslak and International Hospital General Surgery Department between 2010 and 2013 were reviewed retrospectively. Demographic data along with clinicopathological features of the patients and type of surgery were analyzed. Results: Median age of the patients with benign and borderline phyllodes tumors were 35 (24-47) and 31 (21-79), respectively. Median size of the tumor was 3.7cm (1.5-5.5cm) in the benign phyllodes groups and 5.2cm (2.4-12cm) in borderline phyllodes group. Ultrasonography, mammography and breast MRI was used in 13 (100%), 4(37%) and 2 (15.3%) patients, respectively. The majority of the patients underwent excisional biopsy for definitive diagnosis. Three patients (23%) were re- operated to achieve safe surgical margins. In pathological examination, 4 tumors were found to be borderline, and 10 tumors were found to be benign phyllodes tumors. There was no malignant phyllodes tumor. None of the patients has a local or systemic recurrence in a median follow-up of 12 (2-24) months. Conclusıon: Wide excision with safe surgical margins is the preferred therapy as well as it is necessary for precise diagnosis in phyllodes tumors of breast.

Keywords: Phyllodes tumor; breast; excisional biopsy;segmental mastectomy.

MEMENİN FİLLODES TÜMÖRLERİNDE CERRAHİ TEDAVİ

Deniz Eren Boler1, Cihan Uras2, Ercument Gurluler1, Hamit Karayagız3, Yesim Saglıcan4, Alihan Gurkan1, Neslihan Cabıoglu1
1Department of General Surgery, Acıbadem University Medical Faculty, İstanbul, Turkey
2Department of General Surgery, İstanbul University Cerrahpaşa Medical Faculty & Acıbadem Bakırköy Hospital, İstanbul, Turkey
3Department of General Surgery, International Hospital, İstanbul, Turkey
4Department of Pathology Acıbadem University Medical Faculty, İstanbul, Turkey

Amaç: Fillodes tümörleri nadir görülen meme tümörleri olup tanı ve tedavisinde tartışmalar mevcuttur. Bu yazıda kesin tanısı fillodes tümör olan hastalardaki cerrahi yaklaşımımızı ve sonuçlarımızı sunmayı amaçladık. Hastalar ve yöntem: Acıbadem Bakırköy, Maslak ve International Hastaneleri’nde 2010-2013 yılları arasında ameliyat edilen ve kesin tanısı fillodes tümör olan hastaların tıbbi kayıtları retrospektif olarak incelendi. Hastaların demografik ve klinikopatolojik özellikleri ile yapılan cerrahi tipi analiz edildi. Sonuçlar: Hastaların median yaşı, benign ve borderline fillodes grubunda sırasıyla 35 (24-47) ve 31 (21-79) idi. Median tümör çapı benign fillodes grubunda 3.7cm(1.5-5cm) ve borderline grupta 5.2cm (2.4-12cm) idi. Onüç hastada (%100) ultrasonografi, 4 hastada (%37) mammografi ve 2 hastada (%15.3) meme MRI yapıldı. Kesin tanı için hastaların büyük çoğunluğunda eksizyonel biyopsi yapıldı. Üç hasta (%23) güvenli cerrahi sınırı sağlamak için ikinci kez ameliyat edildi. Patolojik incelemede 4 tümör borderline ve 10 tümör benign fillodes tümörü olarak değerlendirildi. Malign fillodes tumor saptanmadı. Median 12 ay (2-24) olan takip süresi sonunda hiç bir hastada local ya da sistemik nüks görülmedi. Sonuç: Güvenli cerrahi sınır ile birlikte geniş eksizyon memenin fillodes tümörlerinin kesin tanısı için gereklidir ve tercih edilen tedavi yöntemidir.

Anahtar Kelimeler: Fillodes tümör; meme; eksizyonel biyopsi; segmental mastektomi.

Deniz Eren Boler, Cihan Uras, Ercument Gurluler, Hamit Karayagız, Yesim Saglıcan, Alihan Gurkan, Neslihan Cabıoglu. SURGICAL MANAGEMENT OF PHYLLODES TUMORS OF BREAST. YMJ. 2013; 7(26): 613-618
Manuscript Language: English
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